Usual IV loading dose: 15 mg/kg TBW Maintenance dose (started 18-24h after load): 6 mg/kg ibw IV/PO in divided doses q8 to 12h
These guidelines are not inclusive of all medications used in the CC and are meant to be used as a guide only
A similar study by the same research team showed that errors during IV bolus administration occurred frequently (73%), the most common of which was bolus doses being injected faster than recommended (95%)
Intravenous push (IV push) is a process of introducing a medication or fluid substance directly into the bloodstream via the venous system
Applies to the following strengths: 50 mg/mL; 50 mg; 100 mg; 30 mg; 25 mg/mL; 200 mg; 300 mg; sodium Usual Adult Dose for: Seizures Status Epilepticus Seizure Prophylaxis During or Following Neurosurgery Usual Pediatric Dose for: Seizures Status Epilepticus July 23, 2015
Like other antiepileptic drugs, DILANTIN may cause suicidal thoughts or This Medication Guide has been approved by the U
Assess the patency of central venous access devices using, at a minimum, a 10 mL diameter-sized syringe filled with preservative-free 0
Care should be taken 1 2 3 Next Tweety, BSN, RN 34,050 Posts Specializes in Med-Surg, Trauma, Ortho, Neuro, Cardiac
Dilantin Dosage and Administration Adult starting dose in patients who have received no previous treatment is one 100 mg DILANTIN extended capsule three times a day, with dose adjustments as necessary
Common Dilantin side effects may include: drowsiness, confusion; slurred speech; Fosphenytoin is a medication used to manage seizures (treatment of generalized tonic-clonic status epilepticus, focal [partial] onset seizures, or generalized onset seizures, and for the prevention and treatment of seizures occurring during neurosurgery)
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Administration Fosphenytoin sodium is dosed in terms of phenytoin sodium equivalents (PE)
Learn about side effects, interactions and indications
The rate of administration for IV phenytoin should be no greater than 50 mg per minute in adults and 1 to 3 mg/kg/min (or 50 mg per minute, whichever is slower) in pediatric patients
Abstract
Status epilepticus : In a patient having continuous seizure activity, as compared to the more common rapidly recurring seizures, i
Phenytoin mixed with NaCl and infused requires a filter
Procedure for Intravenous Infusion - Any phenytoin ordered as intravenous push will be automatically changed to intravenous infusion by pharmacy upon order verification
Check with your doctor or nurse immediately if any of the following side effects occur: More common
2 mg/kg, maximum 10 mg) are effective alternatives to IV lorazepam when IV access is not already established [21,23,31,32]
Higher doses may be required
Subject: Image Created Date: 10/8/2012 9:57:39 AM Side effects: Constipation, dizziness, dry mouth, dysphoria, euphoria, flushing, light-headedness, nausea, pruritus, sweating, and vomiting
What is the most important action for the nurse to take before administering the IV push medication? a
After IV administration to mice, fosphenytoin blocked the tonic phase of maximal electroshock seizures at doses equivalent to those effective for phenytoin
Explanation: To calculate the number of mL to prepare for administration, we can use a simple ratio and proportion
The drug is slowly administered intravenously directly into a large central or peripheral vein through an IV catheter less than 20 gauge, not exceeding a rate of 50 mg/minute
Once maintenance dose is established, twice-daily dosing may be used
Administer in normal saline solutions
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The following adverse effects relate specifically to acute intravenous administration of the phenytoin, and the specific monitoring required
Well-tolerated The rate of IV administration should not exceed 150 mg phenytoin sodium equivalents (PE) per minute in adults and 2 mg PE/kg/min (or 150 mg/PE/min whichever is slower) in pediatric patients because of the risk of severe hypotension and cardiac arrhythmias
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1 mg/kg, at a rate of 2 mg/min
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IV administration of phenytoin
The nurse is preparing to administer phenytoin (Dilantin) intravenous push
The recommended diluent is 0
The amount and concentration of fosphenytoin is always expressed in terms of mg PE
phenytoin should be injected quickly
If mixing medications in a syringe for bolus administration (IV push), assure that they are compatible when combined in a syringe
Dilantin should be diluted in a saline solution and the IV tubing should be flushed before and after administration because a dextrose solution will cause drug precipitation
Loading dose not for administration to patients with a history of renal or hepatic disease; reserve for patients who require rapid steady serum levels, when IV administration not desirable, and for patients in a clinic or
The filter is used to remove crystals and minimize the incidence of phlebitis
IV ADMINISTRATION: LOADING DOSE: 10 to 15 mg/kg by slow IV infusion, not to exceed 50 mg/min MAINTENANCE DOSE: 100 mg orally or IV every 6
risk severe
The following medications require dilution: ranitidine, famotidine, pantoprazole, lorazepam, promethazine
Continuous monitoring of the electrocardiogram, blood pressure, and respiratory
Jul 29, 2006
7 mg/mL, in NS only with in-line filter to decrease precipitation Intravenous Push (IV PUSH) Medications, Adult (PAT030)
The recommended dosage for adult and pediatric patients 6 months of age and older for prevention of nausea and vomiting associated with emetogenic chemotherapy is 0
Assess the condition of the IV insertion site d
5–1 mg/kg/min in neonates due to the risk of hypotension, as noted in a boxed warning in the Check with your doctor or nurse immediately if any of the following side effects occur: More common
Design: A prospective study of patients presenting with acute onset of seizures
In a randomized trial of 898 patients with status epilepticus in the prehospital setting, 10 mg IM midazolam was superior to 4 mg IV lorazepam in adults [ 10 ]
Do not exceed an infusion rate of 50 mg/min
DILANTIN (phenytoin sodium) injection, USP is a sterile solution of 50 mg phenytoin sodium per milliliter for intravenous or intramuscular administration
It is unclear from our data exactly how the administration techniques of intravenous phenytoin may have contributed to the development of PGS
Adult Quick IV Push ED Reference Table
After 2–4 days may ↑ to 25 mg 4 times daily for the rest of the 1st wk; may then ↑ to 50 mg 4 times daily (up to 300 mg/day)
You do not need an infusion pump when administering via IV push, and administration via central lines is
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