Clopidogrel is a platelet inhibitor
Clopidogrel is a pro-drug that is metabolised by cytochrome P450 (CYP) enzymes (including the 3A4 and 2C19 isoforms) to an active thiol metabolite that antagonises the
Clopidogrel is an inactive prodrug; it is converted to its active metabolite through the cytochrome P450 (CYP3A4) pathway, which also metabolizes calcium channel blockers (CCBs)
Clopidogrel is an oral antiplatelet agent used to inhibit blood clots in coronary artery disease, peripheral vascular disease, and cerebrovascular disease, and
Blood pressure therapy for patients with coronary artery disease should start with beta blockers and angiotensin-converting enzyme inhibitors
Tablets are
Myra Skluth answered Specializes in Internal Medicine It prevents platelet
67L/min (1
P2Y12 receptor blockers are another group of antiplatelet drugs
It prevents platelets (a type of blood cell) from sticking together and forming a dangerous blood clot
25 Consider clopidogrel, as part of dual antiplatelet therapy with aspirin, or aspirin alone, for people with acute STEMI not treated with PCI, if they have a high bleeding risk
Beta-blockers can cause lung muscle spasms that make it difficult to breathe
The safety and pharmacodynamic compatibility of clopidogrel with medications commonly used in patients with atherosclerosis, such as, a beta-adrenergic receptor antagonist (atenolol) and a calcium uptake inhibitor (nifedipine) were assessed
For patients otherwise at high risk for bleeding due to prior hemorrhagic stroke, ongoing bleeding, bleeding diathesis, or clinically relevant anemia In one study of metoprolol, researchers looked at the interaction of alcohol and the beta-blocker in a lab
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Liver Clopidogrel is activated in the liver primarily by the hepatic CYP2C19 enzyme system
clopidogrel or glycoprotein IIB/IIIA inhibitor
Angina
Nitrates and calcium channel blockers may be administered to treat anginal symptoms but are not indicated for routine use
Clopidogrel is mostly used by people who don't tolerate ASA well or can't take it for other reasons